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Search Results for " amyloid β "

ターゲット

220

阻害剤

24

天然化合物

22

リコンビナントタンパク質

1

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カタログ番号 製品名 別名 ターゲット
TP1214L β-Amyloid 15-21 acetate Beta-Amyloid (15-21) acetate Beta Amyloid
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.
TP1229 β-Amyloid (1-15) Amyloid β-Protein (1-15) Beta Amyloid
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
TP1786L Amyloid β-Protein 10-20 acetate Amyloid β-Protein 10-20 acetate(152286-31-2 free base) Beta Amyloid
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α...
T7562 β-Amyloid (31-35) β-Amyloid 31-35(TFA),β-Amyloid 31-35 Beta Amyloid
β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.
T35499 β-Amyloid (1-42), (rat/mouse) (TFA) Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
β-Amyloid (1-42), (rat/mouse) (TFA) is a peptide fragment consisting of 42 amino acids that can be used to study Alzheimer's disease.
TP1007L β-Amyloid (1-42), acetate (human) β-Amyloid (1-42), human acetate (107761-42-2 Free base)
β-Amyloid (1-42), acetate (human) is a peptide consisting of 42 amino acids that is part of β-Amyloid and is commonly used in Alzheimer's disease modeling.
TP1866L β-amyloid 1-11 acetate(190436-05-6 free base) Beta Amyloid
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
TP1359L Amyloid β Peptide (42-1)(human) acetate Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base) Beta Amyloid
Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease...
T38149 β-Amyloid (1-43)(human)
The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor ...
T39285 Biotin-β-Amyloid (1-40)
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide.
T37768 β-Amyloid (1-37) (human)
β-Amyloid (1-37) (human) Potentially associated with mental status in Alzheimer's disease.
T37368 Amyloid-β (1-8) Peptide
Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
T37369 Amyloid-β (1-8, A2V) Peptide Amyloid-β (1-8, A2V) Peptide
Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor ...
T39146 β-Amyloid (1-40), FAM-labeled
β-Amyloid (1-40), FAM-labeled, is a β-Amyloid (1-40) peptide tagged with a FAM fluorescent label, exhibiting an excitation wavelength (λ ex) of 492 nm and an emission wavelength (λ em) of 518 nm.
T35498 β-Amyloid (1-14),mouse,rat
β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-se...
T39302 β-Amyloid (1-38), mouse, rat
β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated wi...
TP1227 β-Amyloid (12-28) β-amyloid 12-28,Amyloid β-Protein (12-28)
Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
T37367 Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of ne...
TP1673 β-Amyloid (11-22) β-Amyloid 11-22
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). A...
TP1480 β-Amyloid (12-20) β-Amyloid 12-20
β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects.
TP1599 β-Amyloid (1-34) β-Amyloid 1-34
This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
TP1633 β-Amyloid (18-28) β-Amyloid 18-28
Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting ...
TP1226 β-Amyloid (1-28) Amyloid β-Protein (1-28),β-Amyloid 1-28
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
TP1228 β-Amyloid (1-16) Amyloid β-Protein (1-16),β-Amyloid 1-16
β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is...
TP1225 β-Amyloid (22-35) β-Amyloid 22-35,Amyloid β-Protein (22-35)
β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
TP1303 β-Amyloid (1-40) β-Amyloid 1-40
Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
TP1692 β-Amyloid (13-27) β-Amyloid 13-27
β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta a...
TP1500 β-Amyloid (1-17) β-Amyloid 1-17
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
TP1494 β-Amyloid (4-10) β-Amyloid 4-10
Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.
TP1538 β-Amyloid (1-20) β-Amyloid 1-20
This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
TP1719 β-Amyloid (33-40) β-Amyloid 33-40
β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.
TP1586 β-Amyloid (35-42) β-Amyloid 35-42
β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.
TP1544 β-Amyloid (22-40) β-Amyloid 22-40
This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.
TP1645 β-Amyloid (1-9) β-Amyloid 1-9
This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
TP1866 β-Amyloid (1-11) β-amyloid 1-11
Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.
TP1231 β-Amyloid (29-40) Amyloid beta-protein(29-40),β-Amyloid 29-40
β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusio...
TP1786 β-Amyloid (10-20) Amyloid β-Protein 10-20
Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains ...
TP1214 β-Amyloid 15-21 Beta-Amyloid (15-21)
β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.
T14284 β-Amyloid (25-35) β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35) Beta Amyloid
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
T80037 5-FAM-β-Amyloid (1-28) 5-FAM-Amyloid β-protein (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.
TP1359 β-Amyloid (42-1), human Amyloid β Peptide (42-1)(human)
β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.
T37370 Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red an...
T37472 TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's...
TP1007 β-Amyloid (1-42), human β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human Beta Amyloid
β-Amyloid (1-42), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
T21890 JLK6 Gamma-secretase
JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling
T37200 Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Biotin-amyloid-β (1-42) peptide is an affinity probe that allows amyloid-β (1-42) (Aβ42) to be detected or immobilized through interaction with the biotin ligand. It has been used to identify Aβ42 interaction partners in...
TP1230 β-Amyloid (1-42), (rat/mouse) β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)
Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.
TP1441 β-Amyloid (1-40) (rat) Amyloid β-peptide (1-40) rat
Rat form of the beta-Amyloid (1-40) peptide
T80035 Biotin-β-Amyloid (1-42), human TFA Biotin-amyloid β-peptide (1-42) (human) TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the pathogenesis of Alzheimer's disease [1].
T14199 ALZ-801 Valiltramiprosate Beta Amyloid
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m...

Compounds

β-Amyloid 15-21 acetate
TP1214L
Synonym: Beta-Amyloid (15-21) acetate
Target: Beta Amyloid
β-Amyloid (1-15)
TP1229
Synonym: Amyloid β-Protein (1-15)
Target: Beta Amyloid
Amyloid β-Protein 10-20 acetate
TP1786L
Synonym: Amyloid β-Protein 10-20 acetate(152286-31-2 free base)
Target: Beta Amyloid
β-Amyloid (31-35)
T7562
Synonym: β-Amyloid 31-35(TFA),β-Amyloid 31-35
Target: Beta Amyloid
β-Amyloid (1-42), (rat/mouse) (TFA)
T35499
Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
Target:
β-Amyloid (1-42), acetate (human)
TP1007L
Synonym: β-Amyloid (1-42), human acetate (107761-42-2 Free base)
Target:
β-amyloid 1-11 acetate(190436-05-6 free base)
TP1866L
Synonym:
Target: Beta Amyloid
Amyloid β Peptide (42-1)(human) acetate
TP1359L
Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)
Target: Beta Amyloid
β-Amyloid (1-43)(human)
T38149
Synonym:
Target:
Biotin-β-Amyloid (1-40)
T39285
Synonym:
Target:
β-Amyloid (1-37) (human)
T37768
Synonym:
Target:
Amyloid-β (1-8) Peptide
T37368
Synonym:
Target:
Amyloid-β (1-8, A2V) Peptide
T37369
Synonym: Amyloid-β (1-8, A2V) Peptide
Target:
β-Amyloid (1-40), FAM-labeled
T39146
Synonym:
Target:
β-Amyloid (1-14),mouse,rat
T35498
Synonym:
Target:
β-Amyloid (1-38), mouse, rat
T39302
Synonym:
Target:
β-Amyloid (12-28)
TP1227
Synonym: β-amyloid 12-28,Amyloid β-Protein (12-28)
Target:
Amyloid-β (1-42) Peptide (trifluoroacetate salt)
T37367
Synonym:
Target:
β-Amyloid (11-22)
TP1673
Synonym: β-Amyloid 11-22
Target:
β-Amyloid (12-20)
TP1480
Synonym: β-Amyloid 12-20
Target:
β-Amyloid (1-34)
TP1599
Synonym: β-Amyloid 1-34
Target:
β-Amyloid (18-28)
TP1633
Synonym: β-Amyloid 18-28
Target:
β-Amyloid (1-28)
TP1226
Synonym: Amyloid β-Protein (1-28),β-Amyloid 1-28
Target:
β-Amyloid (1-16)
TP1228
Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16
Target:
β-Amyloid (22-35)
TP1225
Synonym: β-Amyloid 22-35,Amyloid β-Protein (22-35)
Target:
β-Amyloid (1-40)
TP1303
Synonym: β-Amyloid 1-40
Target:
β-Amyloid (13-27)
TP1692
Synonym: β-Amyloid 13-27
Target:
β-Amyloid (1-17)
TP1500
Synonym: β-Amyloid 1-17
Target:
β-Amyloid (4-10)
TP1494
Synonym: β-Amyloid 4-10
Target:
β-Amyloid (1-20)
TP1538
Synonym: β-Amyloid 1-20
Target:
β-Amyloid (33-40)
TP1719
Synonym: β-Amyloid 33-40
Target:
β-Amyloid (35-42)
TP1586
Synonym: β-Amyloid 35-42
Target:
β-Amyloid (22-40)
TP1544
Synonym: β-Amyloid 22-40
Target:
β-Amyloid (1-9)
TP1645
Synonym: β-Amyloid 1-9
Target:
β-Amyloid (1-11)
TP1866
Synonym: β-amyloid 1-11
Target:
β-Amyloid (29-40)
TP1231
Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40
Target:
β-Amyloid (10-20)
TP1786
Synonym: Amyloid β-Protein 10-20
Target:
β-Amyloid 15-21
TP1214
Synonym: Beta-Amyloid (15-21)
Target:
β-Amyloid (25-35)
T14284
Synonym: β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35)
Target: Beta Amyloid
5-FAM-β-Amyloid (1-28)
T80037
Synonym: 5-FAM-Amyloid β-protein (1-28)
Target:
β-Amyloid (42-1), human
TP1359
Synonym: Amyloid β Peptide (42-1)(human)
Target:
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
T37370
Synonym:
Target:
TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
T37472
Synonym:
Target:
β-Amyloid (1-42), human
TP1007
Synonym: β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human
Target: Beta Amyloid
JLK6
T21890
Synonym:
Target: Gamma-secretase
Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
T37200
Synonym:
Target:
β-Amyloid (1-42), (rat/mouse)
TP1230
Synonym: β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)
Target:
β-Amyloid (1-40) (rat)
TP1441
Synonym: Amyloid β-peptide (1-40) rat
Target:
Biotin-β-Amyloid (1-42), human TFA
T80035
Synonym: Biotin-amyloid β-peptide (1-42) (human) TFA
Target:
ALZ-801
T14199
Synonym: Valiltramiprosate
Target: Beta Amyloid
1 2 3 4 5
カタログ番号 製品名 別名 ターゲット
TN6919 Methyl tridecanoate Beta Amyloid , AChE
Methyl tridecanoate is a natural product.
T2212 Geniposide Beta Amyloid , Influenza Virus
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation...
T3914 Saikosaponin C Beta Amyloid , Caspase
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
T8012 Scyllo-Inositol Scyllitol Beta Amyloid , Endogenous Metabolite
Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheimer's disease.
T0795 Rutin Quercetin 3-O-rutinoside,Rutoside Beta Amyloid , Prostaglandin Receptor , Autophagy
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
T4S0350 Licochalcone B Beta Amyloid , Others
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...
TMS1461 Qingyangshengenin B Otophylloside B Beta Amyloid
Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...
T6S1918 Schisantherin B Gomisin-B,Wuweizi ester-B,Schizantherin-B Beta Amyloid , Others
1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
T1686 Hematoxylin Hydroxybrazilin,Natural Black 1,Haematoxylin Beta Amyloid , Others
Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
T2872 Ginsenoside Re Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
T2961 Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1 Apoptosis , ERK , Beta Amyloid
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
T2777 Ginsenoside Rg1 Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2 Apoptosis , Beta Amyloid , NF-κB
Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level i...
T2873 Ginsenoside Rg2 Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2 Beta Amyloid , GSK-3 , NF-κB
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.
T3402 20(S)-Ginsenoside Rg3 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
TN1653 Fustin ERK , Beta Amyloid , AChR
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
T22417 Rutin hydrate Rutoside,Sophorin,Quercetin-3-O-rutinoside Beta Amyloid , Others , Autophagy
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
TN4368 Kaempferol-3,7-di-O-β-glucoside Kaempferol 3,7-di-O-glucoside Glucosidase , Amylase
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...
T3769 Tenuifolin Others , Beta-Secretase , AChE
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
TL0007 Bisdemethoxycurcumin Curcumin III,Didemethoxycurcumin Epigenetic Reader Domain , Wnt/beta-catenin
Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...
T32614 L-Clausenamide (-)-Clausenamide Microtubule Associated
L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...
T79968 Coumarinic acid
Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].
T37957 Setosusin
Setosusin is a meroterpenoid fungal metabolite originally isolated from C. setosus. It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM). In vivo, setosusin (30 mg/kg) induces tre...
T83407 2',3'-Dihydroxy-4',6'-dimethoxychalcone
2',3'-Dihydroxy-4',6'-dimethoxychalcone (compound 1) possesses the capacity to inhibit Amyloid β-protein (Aβ42) fibrillization and aggregation, demonstrating oral activity with detectable presence in the brain [1].

天然物製品

Methyl tridecanoate
TN6919
Synonym:
Target: Beta Amyloid, AChE
Geniposide
T2212
Synonym:
Target: Beta Amyloid, Influenza Virus
Saikosaponin C
T3914
Synonym:
Target: Beta Amyloid, Caspase
Scyllo-Inositol
T8012
Synonym: Scyllitol
Target: Beta Amyloid, Endogenous Metabolite
Rutin
T0795
Synonym: Quercetin 3-O-rutinoside,Rutoside
Target: Beta Amyloid, Prostaglandin Receptor, Autophagy
Licochalcone B
T4S0350
Synonym:
Target: Beta Amyloid, Others
Qingyangshengenin B
TMS1461
Synonym: Otophylloside B
Target: Beta Amyloid
Schisantherin B
T6S1918
Synonym: Gomisin-B,Wuweizi ester-B,Schizantherin-B
Target: Beta Amyloid, Others
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
Hematoxylin
T1686
Synonym: Hydroxybrazilin,Natural Black 1,Haematoxylin
Target: Beta Amyloid, Others
Ginsenoside Re
T2872
Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re
Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK
Notoginsenoside R1
T2961
Synonym: Sanqi glucoside R1,Sanchinoside R1
Target: Apoptosis, ERK, Beta Amyloid
Ginsenoside Rg1
T2777
Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2
Target: Apoptosis, Beta Amyloid, NF-κB
Ginsenoside Rg2
T2873
Synonym: Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2
Target: Beta Amyloid, GSK-3, NF-κB
20(S)-Ginsenoside Rg3
T3402
Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Fustin
TN1653
Synonym:
Target: ERK, Beta Amyloid, AChR
Rutin hydrate
T22417
Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside
Target: Beta Amyloid, Others, Autophagy
Kaempferol-3,7-di-O-β-glucoside
TN4368
Synonym: Kaempferol 3,7-di-O-glucoside
Target: Glucosidase, Amylase
Tenuifolin
T3769
Synonym:
Target: Others, Beta-Secretase, AChE
Bisdemethoxycurcumin
TL0007
Synonym: Curcumin III,Didemethoxycurcumin
Target: Epigenetic Reader Domain, Wnt/beta-catenin
L-Clausenamide
T32614
Synonym: (-)-Clausenamide
Target: Microtubule Associated
Coumarinic acid
T79968
Synonym:
Target:
Setosusin
T37957
Synonym:
Target:
2',3'-Dihydroxy-4',6'-dimethoxychalcone
T83407
Synonym:
Target:

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04693 APLP1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157.
TMPY-03884 Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) Human E. coli
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067...
TMPY-03885 Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) Human E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067...
TMPY-03628 APLP1 Protein, Human, Recombinant (His) Human HEK293 Cells
APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1.
TMPY-02110 Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) Human E. coli
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-02221 Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) Human E. coli
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPJ-00684 SNCA Protein, Mouse, Recombinant (His) Mouse E. coli
Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's ...
TMPJ-00683 SNCA Protein, Mouse, Recombinant Mouse E. coli
SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042.
TMPJ-00023 SNCA Protein, Human, Recombinant (His) Human E. coli
SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840.
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc) Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPJ-00338 LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
TMPJ-00722 APBA3 Protein, Human, Recombinant (His) Human E. coli
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloi...
TMPJ-00851 IDE Protein, Human, Recombinant (His) Human HEK293 Cells
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r...
TMPK-00935 APLP2 Protein, Human, Recombinant (His) Human HEK293 Cells
Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0....
TMPK-01146 LGMN Protein, Human, Recombinant (His) Human HEK293 Cells
Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in th...
TMPK-01065 SEZ6 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00541 SEZ6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPY-03065 BACE2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is th...
TMPK-00996 SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00998 SEZ6 Protein, Human, Recombinant (His) Human HEK293 Cells
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00997 SEZ6 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPJ-00292 CD36 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ...
APLP1 Protein, Mouse, Recombinant (His)
TMPY-04693
Species: Mouse
Expression System: HEK293 Cells
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)
TMPY-03884
Species: Human
Expression System: E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)
TMPY-03885
Species: Human
Expression System: E. coli
APLP1 Protein, Human, Recombinant (His)
TMPY-03628
Species: Human
Expression System: HEK293 Cells
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)
TMPY-02110
Species: Human
Expression System: E. coli
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)
TMPY-02221
Species: Human
Expression System: E. coli
SNCA Protein, Mouse, Recombinant (His)
TMPJ-00684
Species: Mouse
Expression System: E. coli
SNCA Protein, Mouse, Recombinant
TMPJ-00683
Species: Mouse
Expression System: E. coli
SNCA Protein, Human, Recombinant (His)
TMPJ-00023
Species: Human
Expression System: E. coli
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
TMPY-00668
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00338
Species: Human
Expression System: HEK293 Cells
APBA3 Protein, Human, Recombinant (His)
TMPJ-00722
Species: Human
Expression System: E. coli
IDE Protein, Human, Recombinant (His)
TMPJ-00851
Species: Human
Expression System: HEK293 Cells
APLP2 Protein, Human, Recombinant (His)
TMPK-00935
Species: Human
Expression System: HEK293 Cells
LGMN Protein, Human, Recombinant (His)
TMPK-01146
Species: Human
Expression System: HEK293 Cells
SEZ6 Protein, Mouse, Recombinant (His)
TMPK-01065
Species: Mouse
Expression System: HEK293 Cells
SEZ6 Protein, Cynomolgus, Recombinant (His)
TMPK-00541
Species: Cynomolgus
Expression System: HEK293 Cells
BACE2 Protein, Mouse, Recombinant (His)
TMPY-03065
Species: Mouse
Expression System: HEK293 Cells
SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00996
Species: Human
Expression System: HEK293 Cells
SEZ6 Protein, Human, Recombinant (His)
TMPK-00998
Species: Human
Expression System: HEK293 Cells
SEZ6 Protein, Human, Recombinant (hFc)
TMPK-00997
Species: Human
Expression System: HEK293 Cells
CD36 Protein, Human, Recombinant (hFc)
TMPJ-00292
Species: Human
Expression System: HEK293 Cells
カタログ番号 製品名
L9840 Anti-Alzheimer's Disease Compound Library

986 compounds
A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.